Alcohols and polyols

Organic compounds containing one or more hydroxyl functional groups bonded to a carbon atom; hydroxyls consist of an oxygen atom bonded to a hydrogen atom. Alcohols exist in chain, or as closed rings. Polyols contain two or more hydroxyl groups.

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4,756 – 4,770 of 5,342 results

4,756

Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | MFCD04038020 | 98.43% | C19H18ClN5O7S3 | 100 MG

Ceftiofur hydrochloride is an inhibitor of bacterial cell wall synthesis that targets bacterial penicillin-binding proteins (PBPs). It exhibits anti-inflammatory effects in endotoxemia. Its bactericidal action stems from inhibiting the synthesis of bacterial cell wall peptidoglycan, leading to bacterial cell lysis. Additionally, Ceftiofur hydrochloride can inhibit the activation of NF-κB and MAPKs, which consequently reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Targets bacterial penicillin-binding proteins (PBPs).
Exhibits bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis.
Leads to bacterial cell lysis.
Possesses anti-inflammatory properties by inhibiting NF-κB and MAPK activation.
Reduces the secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6).

Pricing & Availability

4,757

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG

Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM, showing high selectivity for AChE over BuChE. It exhibits a neuroprotective effect on Aβ42 neurotoxicity. In vivo, Donepezil treatment prevents the progression of scopolamine-induced memory impairment in mice, demonstrating its potential in neurodegenerative research.

Reversible, selective AChE inhibitor
IC50 of 6.7 nM for AChE activity
High selectivity for AChE over BuChE
Exhibits a neuroprotective effect on Aβ42 neurotoxicity
Enhances phosphorylation of Akt and GSK-3β
Reduces phosphorylation of tau and glycogen synthase
Increases cell viability in cortical neuronal cells
Prevents scopolamine-induced memory impairment in mice

Pricing & Availability

4,758

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 25 MG

Dopexamine hydrochloride is a β2 adrenergic receptor agonist and a dopamine analogue. It exhibits agonist activity at β2 and dopaminergic receptors, attenuating systemic inflammatory response, reducing tissue leukocyte infiltration, and protecting against organ injury. It can reduce the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without significantly altering systemic hemodynamics.

Agonist activity at β2 and dopaminergic receptors
Attenuates systemic inflammatory response
Reduces tissue leukocyte infiltration
Protects against organ injury
Stimulates β-adrenergic and dopamine 1 and 2 receptors
Confers vasodilatory effects

Pricing & Availability

4,759

Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG

Aplaviroc hydrochloride is a potent CCR5 antagonist, effective against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM. It also suppresses the infectivity and replication of HIV-1MDR variants at low concentrations. This compound binds to CCR5 with high affinity and has been shown to suppress R5 HIV-1 viremia in animal models. Aplaviroc hydrochloride has been involved in multiple clinical trials for HIV infection.

Potent CCR5 antagonist
Effective against wild-type R5 HIV-1 strains
Suppresses HIV-1MDR variants
Binds to CCR5 with high affinity
Suppresses R5 HIV-1 viremia in animal models
Investigated in clinical trials for HIV infection

Pricing & Availability

4,760

Medchemexpress LLC Endoxifen (hydrochloride) | 1197194-41-4 | 98.0% | 409.95 | 100 MG

Endoxifen hydrochloride is a key active metabolite of Tamoxifen with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. It has potential for breast cancer study.

More potent ER antagonist than tamoxifen.
Induces ER-alpha degradation and inhibits ER transcriptional activity.
Targets estrogen receptor α for degradation in breast cancer cells, inhibiting proliferation.
Exhibits strong growth inhibitory and cytotoxic effects on breast cancer cell lines at 10 μM.
Rapidly absorbed and systemically available; leads to higher exposure levels than tamoxifen.
Safe and effective in inhibiting human mammary tumor xenografts in female mice orally.

Pricing & Availability

4,761

Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 100 MG

GYKI 53655 hydrochloride is a research-grade small molecule that acts as a non-competitive antagonist of AMPA and kainate receptors. It is supplied as a light yellow to yellow solid with reported purity of ~98.4% and molecular formula C19H21ClN4O3. Intended for in vitro research use only.

Non-competitive AMPA and kainate receptor antagonist.
High purity (~98.4%) for consistent experimental results.
Light yellow to yellow solid, soluble in DMSO and water with recommended handling precautions.
Recommended storage: solid at 4°C; prepared solutions at -80°C (up to 6 months) or -20°C (short term).
Available in multiple solid sizes, including 100 mg, for lab-scale studies.

Pricing & Availability

4,762

Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML

SB-612111 hydrochloride is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with high affinity for hORL-1 (Ki = 0.33 nM). It demonstrates selectivity for μ-, κ-, and δ-receptors. This compound effectively antagonizes the pronociceptive action of Nociceptin in an acute pain model.

Potent ORL-1 antagonist with high affinity.
Exhibits selectivity for μ-, κ-, and δ-receptors.
Effectively antagonizes pronociceptive action of Nociceptin.
Demonstrates antihyperalgesic effects in animal models.

Pricing & Availability

4,763

Medchemexpress LLC EPZ011989 (hydrochloride) | 2095432-26-9 | 99.4% | 642.27 | 25 MG

EPZ011989 hydrochloride is a potent and orally active Zeste Homolog 2 (EZH2) inhibitor. It demonstrates anti-tumor activity and functions as a click chemistry reagent. It is intended for research use only.

Potent and orally active EZH2 inhibitor
Ki value of <3 nM
Shows anti-tumor activity
Functions as a click chemistry reagent (contains an Alkyne group for CuAAc)

Pricing & Availability

4,764

Medchemexpress LLC SRI-011381 hydrochloride | 2070014-88-7 | 99.6% | 365.94 g/mol | C20H32ClN3O | 1 G

SRI-011381 hydrochloride is a small-molecule, orally active agonist of the TGF-β/Smad signaling pathway with reported neuroprotective effects. Supplied as the hydrochloride salt for research use, the compound is characterized by a defined molecular weight and high reported purity suitable for in vitro and in vivo studies.

Orally active TGF-β signaling agonist.
Reported neuroprotective effects in preclinical studies.
Supplied as the hydrochloride salt for improved handling and solubility.
High reported purity (99.55%).
Molecular weight 365.94 g/mol.
For research use only.

Pricing & Availability

4,765

Medchemexpress LLC SGK1-IN-3 hydrochloride | 00-00-0 | 96.7% | C23H21Cl3N6O3S | 10MG

SGK1-IN-3 hydrochloride is a research-grade small-molecule inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1), reported to inhibit SGK1 with an IC50 of <1 μM. Supplied as the hydrochloride salt, it is intended for biochemical and cell-based research applications, including studies of signaling pathways related to osteoarthritis.

Potent SGK1 inhibition (IC50 <1 μM).
Hydrochloride salt form for improved solubility.
Suitable for biochemical and cell-based assays.
High reported purity (~96.7%).
Available in small research pack sizes for laboratory use.

Pricing & Availability

4,766

Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG

Adrogolide hydrochloride is a research-grade prodrug converted rapidly in plasma to the dopamine D1 receptor agonist A-86929. Supplied as the hydrochloride salt, it is intended for laboratory research use only and is provided in pre-weighed quantities for assay preparation.

High purity (≈99.6%) suitable for research applications.
Molecular weight 435.96 and formula C22H26ClNO4S.
Available in pre-weighed small quantities for in vitro and in vivo studies.
Soluble in DMSO for assay preparation.
Acts as a prodrug to the D1 receptor agonist A-86929.

Pricing & Availability

4,767

Medchemexpress LLC Olcegepant hydrochloride | 586368-06-1 | MFCD07772306 | 99.1% | 906.11 | C38H47Br2N9O5·HCl | 50 MG

Olcegepant hydrochloride is a potent, selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor, provided as the hydrochloride salt for preclinical research use. The compound is supplied with reported high purity and is offered in multiple quantities and solution formats for laboratory studies.

Potent, selective antagonist of the CGRP1 receptor.
Reported high purity (~99.1%).
Available in multiple sizes, including 5 mg-500 mg, and as DMSO solutions.
Molecular formula C38H47Br2N9O5·HCl; molecular weight 906.11 g/mol.
For research use only; not for human or clinical use.

Pricing & Availability

4,768

Medchemexpress LLC Lidocaine hydrochloride hydrate | 6108-05-0 | 99.8% | 100 MG

Lidocaine hydrochloride hydrate inhibits sodium channels involving complex voltage and using dependence. It decreases growth, migration, and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. It is an amide derivative with potential for the research of ventricular arrhythmia.

Inhibits sodium channels
Decreases growth, migration, and invasion of gastric carcinoma cells
Up-regulates miR-145 expression
Inactivates MEK/ERK and NF-κB signaling pathways
Potential for research of ventricular arrhythmia
Causes completely reversible tail nerve block in rats
Decreases cell proliferation in human gastric cancer cell line MKN45
Inhibits MKN45 cell viability
Increases apoptotic cell rate in MKN45 cells
Down-regulates Cyclin D1 and up-regulates p21 expression

Pricing & Availability

4,769

Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG

SSR180711 hydrochloride is an orally active, selective, and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. It acts on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). This compound increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus. It is intended for research use only.

Orally active
Selective and reversible α7 n-AChRs partial agonist
Increases glutamatergic neurotransmission, ACh release, and long-term potentiation (LTP) in the hippocampus
Selective for the α7 receptor subtype compared to α4β2, α3β2, α3β4, and α1β1γδ human n-AChR subtypes (IC50>5 μM)
Rapidly penetrates into the brain (ID50=8 mg/kg; p.o.)

Pricing & Availability

4,770

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.97% | 25 G

Ninhydrin is a chromogenic analytical probe used for the quantification of amino acids and proteins. It reacts with primary and secondary amines, producing a characteristic blue or purple reaction product: diketohydrindylidene-diketohydrindamine. Most amino acids, with the exception of proline, can be hydrolyzed and subsequently quantified colorimetrically following chromatographic separation. This product, appearing as a white to light yellow solid, is intended for research use only and has not been fully validated for medical applications.

Chromogenic analytical probe for the quantification of amino acids and proteins.
Reacts with primary and secondary amines.
Produces a blue or purple reaction product.
Suitable for the colorimetric quantification of most amino acids after chromatographic separation.

Pricing & Availability

Alcohols and polyols

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Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | MFCD04038020 | 98.43% | C19H18ClN5O7S3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Donepezil Hydrochloride | 120011-70-3 | 99.9% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dopexamine hydrochloride | 86484-91-5 | 429.42 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Aplaviroc hydrochloride | 461023-63-2 | 99.9% | 614.17 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Endoxifen (hydrochloride) | 1197194-41-4 | 98.0% | 409.95 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SB-612111 hydrochloride | 99.6% | 454.86 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EPZ011989 (hydrochloride) | 2095432-26-9 | 99.4% | 642.27 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SRI-011381 hydrochloride | 2070014-88-7 | 99.6% | 365.94 g/mol | C20H32ClN3O | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SGK1-IN-3 hydrochloride | 00-00-0 | 96.7% | C23H21Cl3N6O3S | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Adrogolide hydrochloride | 166591-11-3 | 99.6% | 435.96 | C22H26ClNO4S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olcegepant hydrochloride | 586368-06-1 | MFCD07772306 | 99.1% | 906.11 | C38H47Br2N9O5·HCl | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lidocaine hydrochloride hydrate | 6108-05-0 | 99.8% | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ssr180711 (hydrochloride) | 446031-79-4 | 99.9% | 361.66 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Ninhydrin | 485-47-2 | 99.97% | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More